The website uses cookies to allow us to better understand how the site is used. By continuing to use this site, you consent to this policy. Click to learn more.      

Agilent Bio Mab - 1.7µm

Thorough characterization of monoclonal antibodies includes the identification and monitoring of acidic and basic isoforms. The Agilent Bio MAb HPLC columns feature a unique resin specifically designed for high-resolution charge-based separations of monoclonal antibodies. Bio MAb columns are available in 1.7μm, 3μm, 5μm, and 10μm sizes, providing higher resolution with the smaller particles. The Bio MAb column features a highly uniform, densely packed, weak cation exchange layer. This layer of the Bio MAb column is chemically bonded to the hydrophilic, polymeric coating of the Bio MAb column.

  • A packing support composed of a rigid, spherical, highly cross-linked polystyrene divinylbenzene (PS/DVB) non-porous bead
  • Particles grafted with a hydrophilic, polymeric layer, virtually eliminating non-specific binding of antibody proteins
  • A different process is used to layer the weak cation-exchange phase to the particle making it a higher density than the Agilent Bio WCX column particles
  • Specifically designed for the separation of charge isoforms of monoclonal antibodies

Application Note - Analysis of Intact and C-terminal Digested IgG1 on an Agilent Bio MAb 5µm Column

Application Note - pH Gradient Elution for Improved Separation of Monoclonal Antibody Charge Variants


Agilent Bio MAb 1.7µm, 4.6 x 50mm (Stainless Steel), ea. Agilent Bio MAb 1.7µm, Guard 4.0 x 10mm (Stainless Steel), ea.
Part Number: AT-5190-2401
Part Number: AT-5190-2402
price on request
price on request



Welcome at BGB