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Syringe Filters

Simplify Sample Prep and protect Analytical Equipment using Syringe Filters

• Cost-effective, reliable filtration

• Protect analytical columns and instruments

• Achieve more reproducible analyses

The importance of clean sample extracts in maintaining analytical instrumentation cannot be overstated. Particulates commonly found in extracts can quickly damage instrument components, causing costly down time and repair. Chromatographic columns, injectors, detectors, and small diameter tubing are easily plugged by particulates. Even if plugging does not occur, the slow accumulation of particles over time can affect flow rates and create interferences that reduce overall reproducibility. Clean extracts will greatly extend the life of costly chromatographic columns and replacement parts, particularly for HPLC systems. Sample clean-up to remove particulates can be accomplished through the use of inexpensive and easy-to-use syringe filters. These membranes vary in properties and should be selected based on matrix and solvent characteristics. With a female luer lock inlet and male slip outlet, the syringe filter easily fits onto the end of the disposable syringe containing the sample, as shown in Figure 1. The extract is gently pushed through the filter into a sample vial for injection, removing damaging particulates from the final extract. This connection can be further strengthened by using a syringe with a luer lock tip, creating a more secure connection that can withstand higher filtration pressure. With a variety of syringe filters available, understanding the role of diameter, pore size, and membrane will aid in proper selection. Sample volume will determine the choice of diameter, ensuring that the filter is not overloaded. Porosity is dependent on application and, in the case of HPLC, the particle size of the column packing.

Membrane Chemical Compatibility Chart


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