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Knitted Open Tubular (KOT) Reactor

The Biotech knitted open tubular (KOT) reactors are made from tubing which has been knitted into a tortuous path to force the fast moving centre of the liquid stream to mix radially with the slower moving boundary liquid layer, thereby minimizing the axial dispersion. The shape of a chromatographic peak entering the reactor is thus preserved very efficiently. To ensure a stable radial mixing within the KOT, a linear flow rate of 10 cm/s or more is recommended. The KOT reactor is usually the most optimal delay element for use in analytical flow systems, and is typically inserted in the flow path to create a delay line, so that a reaction or other event that requires a certain time can take place. Different delay or reaction times are accomplished by changing the inner diameter and length of the KOT, takin the flow rate through the KOT into consideration.

Biotech KOT reactors can be applied as a delay line in chromatographic separations. One example being the parallel coupling of a MS detector and a fraction collector in preparative separations. The delay time induced by the KOT allows the detector to analyse the eluate and make intelligent decisions of when a new fraction is going to be initiated, without loss of chromatographic efficiency. The Biotech KOT reactors can also be used in post-column reaction detection in HPLC, using both room temperature and heated chemistries. In this set-up the KOT also ensure thorough mixing between the column effluent and the added reagents. Typical reactions are the production of fluorescent products from reactions between eluted compounds and reagents without native fluorescence.


Part Number

Products

Price

Qty / Buy

BT-3000-133 Knitted Open Tubular (KOT) Reactor, PTFE, 10m, 0.25mm ID, ea. price on request
BT-3000-135 Knitted Open Tubular (KOT) Reactor, PTFE, 10m, 0.50mm ID, ea. price on request
BT-3000-138 Knitted Open Tubular (KOT) Reactor, PTFE, 10m, 0.75mm ID, ea. price on request
BT-3000-123 Knitted Open Tubular (KOT) Reactor, PTFE, 1m, 0.25mm ID, ea. price on request
BT-3000-125 Knitted Open Tubular (KOT) Reactor, PTFE, 1m, 0.50mm ID, ea. price on request
BT-3000-128 Knitted Open Tubular (KOT) Reactor, PTFE, 1m, 0.75mm ID, ea. price on request
BT-3000-223 Knitted Open Tubular (KOT) Reactor, PTFE, 2m, 0.25mm ID, ea. price on request
BT-3000-225 Knitted Open Tubular (KOT) Reactor, PTFE, 2m, 0.50mm ID, ea. price on request
BT-3000-228 Knitted Open Tubular (KOT) Reactor, PTFE, 2m, 0.75mm ID, ea. price on request
BT-3000-423 Knitted Open Tubular (KOT) Reactor, PTFE, 4m, 0.25mm ID, ea. price on request
BT-3000-425 Knitted Open Tubular (KOT) Reactor, PTFE, 4m, 0.50mm ID, ea. price on request
BT-3000-428 Knitted Open Tubular (KOT) Reactor, PTFE, 4m, 0.75mm ID, ea. price on request
BT-3000-525 Knitted Open Tubular (KOT) Reactor, PTFE, 5m, 0.50mm ID, ea. price on request
BT-KIT-KOT KOT Connection Kit (to connect 2 KOTs), ea. price on request
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