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HILIC (Hydrophilic Interaction Liquid Chromatography) is a separation mode achieved through the partitioning of polar solutes from high concentration, water-miscible, organic mobile phase into hydrophilic surface environment. Welch Ultisil HILIC Amide column is a special column designed for HILIC mode. As amide group has strong hydrophilicity, stability
and electrically neutral, Ultisil® Amide has longer life, better separation repeatability and peak shape than NH2 phase does.
Based on silica bonded with amide groups, appropriate for the separation of hydrophilic samples
Multiple actions such as hydrogen bond, molecular and electrostatic interactions
Good compatibility with many kinds of detectors, such as MS detector
Stable in organic mobile phase that contains water
