VDSpher MS 100 C8-B-DE Series

Mass spectrometry is becoming more and more crucial as an online detection method. The requirements of the LC/MS analytics are reflected in the conception of HPLC columns. To reduce the solvent quantity and so as not to endanger the vacuum created in the mass spectrometer, columns of smaller dimensions are normally preferred. To profit from a high resolution further, silica gel with a small particle size is recommended for the column. VDSpher MS satisfies this requirement with 2.5µm separation phases. If the resolution is not crucial, VDSpher MS columns with 4µm silica gels are also available.

In principle, any VDSpher column can be used for LC/MS. Because as a sensitive detection method, mass spectrometry is in a position to display very low impurities, depending on the application e.g., carry-overs from previous runs (“carry-over effect“). VDSpher MS phases are selected specially to avoid these effects. In all, ten different modifications are available. The C18 phases enable a large bandwidth of hydrophilic (C18-H, C18-LC-H) and hydrophobic (C18-DE, C18-B-DE) applications. The not endcapped phase C18-B has medium hydrophobicity. Additionally, there are hydrophobic VDSpher MS phases with C8, C4, Phenyl and CN modifications. VDSpher MS phases are available with a pore size of 100Å.

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