Whelk-O2 Series

The Regis Whelk-O 2 is the covalent trifunctional version of the Whelk-O 1. The Whelk-O 2 retains the same chiral selector but modifies the support to silica from a monofunctional linkage to a trifunctional. In most cases, the enantioselectivity remains the same allowing the separation of the analogous family of racemates as does the Whelk-O 1. Whelk-O 2 was designed to enhance the stability of the stationary phase due to hydrolysis while using strong organic modifiers such as trifluoroacetic acid. The Whelk-O 2 is ideal for preparative separations since the material is bonded on 10μm 100Å spherical Kromasil silica. This allows the preparative chromatographer to perform method development on their analytical column and immediately scale-up to larger diameter columns.

Chiral Selector: 1-(3,5-dinitrobenzamido)-1,2,3,4-tetrahydrophenanthrene