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Inertsil ODS-3 is still GL Sciences’ most popular phase and continues to be used widely and reliably for long established methods in pharmaceutical, and contract research labs. Inertsil ODS-3 is ideally modified with Octadecyl groups and endcapped. It provides stronger hydrophobic interactions than other ODS columns and retain a variety of compounds. In addition, the introduction of higher surface area silica provide high preparative loading capacity without sacrificing peak shape.