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Welchrom® C8/SCX Mixed Mode SPE product formed by a C8 alkyl stationary phase change stationary phase SCX with a silica based strong cation in an optimized proportion, which provides a dual retention mechanism. C8 can interact with the hydrophobic part of the analyte, while SCX can interact with the protonated amino part of the analyte. Due to the strong dual interaction between the adsorbent and the analyte, stronger flushing solvents and conditions are allowed to be used to remove the interferences adsorbed on the adsorbent.
