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As aminopropyl groups bonded SPE packing materials, Welchom® NH2 can be used as either a polar adsorbent or a weak anion exchanger. When activated with nonpolar solvents such as n-hexane, it can form hydrogen bonds with any molecule containing -OH, -NH or -SH groups. In water-based environment, pH<7.8 can be used as a weak anion exchanger.