Fortis SpeedCore HILIC 80Å Series

Fortis Speedcore HILIC increases efficiency and retention of polar analytes which do not retain well in reversed phase chromatography. Extended retention is obtained by the partitioning, ion-exchange and hydrogen bonding that can occur on a HILIC stationary phase. Hydrophilic Interaction Chromatography works in a similar way to normal phase chromatography. A polar surface combined with a non-polar mobile phase, typically ACN allows for partition of polar analytes. Retention and resolution are optimised by remembering that ACN is a weak solvent and Water is a strong solvent in HILIC mode.