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Bond Elut SCX



Ion Exchange Silica SPE
Ion exchange phases are more dependent on pH, ionic strength, and counter-ion strength than on solvent strength. These phases depend on ionic interactions as the primary retention mechanism.

  • Useful for compounds with both cationic and non-polar characteristics
  • Superior clean up from a single sorbent
  • Very low pKa ligand elicits strong analyte interaction

Bond Elut SCX is a strong cation exchanger with a very low pKa. Although the pKa is similar to Bond Elut PRS, the presence of the benzene ring in the functional group increases the potential for non-polar interactions. This non-polar characteristic becomes particularly important when conducting ion-exchange from aqueous systems, where selectivity towards compounds exhibiting cationic and non-polar character is seen.


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